ASAPS formed an ad hoc committee to further investigate the pros and cons of mesotherapy, he says. "We don't know whether it works or not because it is used by a lot of people who inject all kinds of chemicals into the skin," Fodor explains. "Our committee looked at the literature and we found no uniformity to what is being used, how much is being injected, and where it is being injected, so we could not draw any conclusions," he says. That's why ASAPS is conducting a clinical trial at five centers to definitively answer questions about mesotherapy. "We will do some studies with an exact and rigid protocol so we can compare apples to apples, not apples to oranges," he says.
While some of these problems still occur (notably the need for transfusions), experts say it's on a much smaller scale in the last few years. In a study presented in 2003 at an American Society of Plastic Surgeons conference in San Diego, researchers found that many such complications could be avoided if patients allowed more time to elapse between weight loss surgery and plastic surgery.
Fodor is more enthusiastic about the LipoSonix technology. "I am very optimistic," he says." I love the results," he says citing as much as a 7-centimeter reduction in waist circumference seen in clinical trials conducted in Mexico. This technology, which uses high-intensity ultrasound waves, beamed about an inch under the skin to break up fatty tissue, has been studied in both pig models and in 33 people in Mexico, he says. The company has applied for FDA status to begin preclinical studies in the U.S. and expects such trials to begin in 2007.
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"I would like to say it is ready to replace liposuction, but it's not -- yet," he says. Still it does have certain benefits over liposuction namely that a person can have the treatment and go to lunch afterward, Fodor says. Unlike liposuction, the new technology does not involve pain, scars, anesthesia, or a long recovery time. Only some topical anesthesia is used, he says.
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