*In the U.S., the CoolSculpting®procedure is FDA-cleared for the treatment of visible fat bulges in the submental area, thigh, abdomen and flank, along with bra fat, back fat, underneath the buttocks (also known as banana roll), and upper arm. It is also FDA-cleared to affect the appearance of lax tissue with submental area treatments. In China, the cryolipolysis system is used for fat layer reduction of the abdomen and flanks. In Taiwan, the CoolSculpting procedure is cleared for the breakdown of fat in the flank (love handle), abdomen, and thigh. Outside the U.S., China and Taiwan, the CoolSculpting procedure for non-invasive fat reduction is available worldwide. CoolSculpting® and its design are trademarks of ZELTIQ Aesthetics, Inc., an Allergan affiliate. CoolSculpting is the treatment doctors use most for non-invasive fat removal.
CoolSculpting works by taking advantage of the fact that fat cells are more sensitive to cold than the other cells around them. This basic scientific fact was first discovered in 1970 by doctors observing children who sucked on popsicles for hours, and ended up having first soreness, and later dimples, caused by loss of fat cells! Fast forward about 20 years, and Harvard scientists revisited this fact, and realized that they could turn this science into a system for aesthetic sculpting of fatty bulges. The key was to find the ‘sweet spot’ of time and temperature, which would kill some fat cells but not damage surrounding structures such as skin. They called the public company that makes the systems Zeltiq. The proof of the success of this concept and treatment: Zeltiq was bought out by Allergan in 2016 for whopping 2.5 billion! This was the largest sale of a single medical device company in history.
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